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Invitrogen™ SUV420H1 Polyclonal Antibody

Product Code. 15564492
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Quantity:
100 μL
Unit Size:
100µL
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15564492 100 μL 100µL
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Product Code. 15564492 Supplier Invitrogen™ Supplier No. PA540926

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Description

Rabbit Polyclonal Antibody

Peptide sequence: NNGFNSGSGS SSTKLKIQLK RDEENRGSYT EGLHENGVCC SDPLSLLESR Sequence homology: Dog: 86%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 91%; Rat: 93%.

Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUV420H1
Applications Immunohistochemistry (Paraffin), Western Blot, Surface Plasmon Resonance
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene KMT5B
Gene Accession No. Q4FZB7
Gene Alias [histone H4]-lysine20 N-methyltransferase KMT5B; [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; AA117471; C630029K18Rik; CGI85; CGI-85; histone-lysine N-methyltransferase KMT5B; histone-lysine N-methyltransferase SUV420H1; Kmt5b; lysine (K)-specific methyltransferase 5B; lysine methyltransferase 5B; lysine N-methyltransferase 5B; Lysine-specific methyltransferase 5B; MGC118906; MGC118909; MGC21161; MGC703; si:dkey-12e7.2; Su(var)4-20 homolog 1; suppressor of variegation 4-20 homolog 1; suppressor of variegation 4-20 homolog 1 (Drosophila); suppressor of variegation 4-20 protein-like 1; SUV420; SUV420H1; suv4-20h1; Unknown (protein for MGC:137299); wu:fb97g06; wu:fi57g03; zgc:103527
Gene Symbols KMT5B
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human SUV420H1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51111
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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