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Invitrogen™ STAR Polyclonal Antibody
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Product Code. 15743501 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15743501 100 μL 100µL
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Product Code. 15743501 Supplier Invitrogen™ Supplier No. PA555581

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TCVLAGMATD FGNMPEQKGV IRAEHGPTCM VLHPLAGSPS KTKLTWLLSI DLKGWLPKSI INQVLSQTQV DFAN Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

Steroidogenic acute regulatory protein (StAR) plays a significant role in cholesterol transport from the cytoplasmic outer membrane to the inner mitochondrial membrane. The 37 kDa precursor is cleaved to generate an active 28 kDa protein capable of facilitating cholesterol metabolism into pregnenolone. StAR is prevalently expressed in mitochondria of steroid-producing adrenal and gonadal tissue. Abnormalities in StAR gene expression are impacted in autosomal Lipoid Congenial Adrenal Hyperplasia (LCAH) resulting in defects in pregnenolone and cortisol synthesis. The mechanism of cholesterol binding to StAR has yet to be elucidated.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STAR
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene STAR
Gene Accession No. P49675
Gene Alias AV363654; cholesterol trafficker; D8Ertd419e; lipid transporter; luteinizing hormone-induced protein; mitochondrial steroid acute regulatory protein; STAR; StAR related lipid transfer (START) domain containing 1; stARD1; StAR-related lipid transfer (START) domain containing 1; START domain containing 1; START domain-containing protein 1; steroid acute regulatory protein; steroidogenic acute regulator; steroidogenic acute regulatory protein; steroidogenic acute regulatory protein, mitochondrial; testis secretory sperm-binding protein Li 241mP
Gene Symbols STAR
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human STAR. Recombinant protein control fragment (Product #RP-93804).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6770
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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