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Invitrogen™ SPOPL Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5113928
Description
Immunogen sequence: WNSNQATDIM ETSGWKSMIQ SHPHLVAEAF RALASAQCPQ FGIPRKRLKQ For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%.
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP.
Specifications
| SPOPL | |
| Polyclonal | |
| Unconjugated | |
| SPOPL | |
| BTBD33; HIB homolog 2; roadkill homolog 2; speckle type BTB/POZ protein like; speckle type POZ protein like; speckle-type POZ protein-like; SPOPL | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 339745 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| Q6IQ16 | |
| SPOPL | |
| Synthetic peptide directed towards the middle region of human SPOPL. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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