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Invitrogen™ SMEK1 Polyclonal Antibody
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Product Code. 16559921
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Quantity:
100 μL
Unit Size:
100µL
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16559921 100 μL 100µL
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Product Code. 16559921 Supplier Invitrogen™ Supplier No. PA597089

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR TLEDEEEMWF NTDEDDMEDG EAVVSPSDKT KNDDDIMDPI SKFMERKKLK ESEEKEVLLK TNLSGRQSPS FKLSLSSGTK TNLTSQSSTT NLPGSPGSPG SPGSPGSPGS VPKNTSQTAA ITTKGGLVGL VDYPDDDEDD DEDEDKEDTL PLSKKAKFDS; Positive Samples: HeLa, HepG2, Jurkat, MCF-7, Mouse spleen, Rat brain; Cellular Location: Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center.

Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMEK1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.71 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PPP4R3A
Gene Accession No. Q6IN85, Q6P2K6
Gene Alias 1110034C04Rik; BC064465; FLFL1; KIAA2010; mKIAA2010; MSTP033; PP4R3; PP4R3A; Ppp4r3a; protein phosphatase 4 regulatory subunit 3A; protein phosphatase 4, regulatory subunit 3A; RGD1309059; serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1; SMEK homolog 1, suppressor of mek1; SMEK homolog 1, suppressor of mek1 (Dictyostelium); SMEK1; smk1; smk-1
Gene Symbols PPP4R3A
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 395-594 of human SMEK1 (NP_0012712101).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 314388, 55671, 68734
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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