missing translation for 'onlineSavingsMsg'
Learn More
Learn More
SMAD2/SMAD3 Rabbit anti-Human, Unconjugated, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA5110396
This item is not returnable.
View return policy
Description
Sequence of this protein is as follows: MSSILPFTPP IVKRLLGWKK GEQNGQEEKW CEKAVKSLVK KLKKTGQLDE LEKAITTQNV NTKCITIPRS LDGRLQVSHR KGLPHVIYCR LWRWPDLHSH HELRAMELCE FAFNMKKDEV CVNPYHYQRV ETPVLPPVLV PRHTEIPAEF PPLDDYSHSI PENTNFPAGI EPQSNIPETP PPGYLSEDGE TSDHQMNHSM DAGSPNLSPN PMSPAHNNLD LQPVTYCEPA
Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad proteins.
Specifications
| SMAD2/SMAD3 | |
| Polyclonal | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P84022, Q15796 | |
| SMAD2, SMAD3 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human SMAD3 (NP_005893.1). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| SMAD3 | |
| 7120426M23Rik; AU022421; hMAD-2; hSMAD2; HSPC193; HsT17436; JV15-2; JV18; JV18-1; LDS1C; LDS3; MAD homolog 2; MAD homolog 3; Mad protein homolog; mad3; MADH2; MADH3; Madr2; Mad-related protein 2; mMad2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic homolog 3; pSMAD2; SMAD; SMAD 2; SMAD 3; SMAD family member 2; SMAD family member 3; Smad2; Smad-2; Smad3 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 4087, 4088 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction