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SERINC3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16879794 Shop All Proteintech Products
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20 μL
150 μL
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150µL
20µL
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16879794 20 μL 20µL
16869794 150 μL 150µL
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Product Code. 16879794 Supplier Proteintech Supplier No. 202671AP20UL

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Rabbit Polyclonal Antibody

The antibody is specific to SERINC3.

TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to maligt tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.

Specifications

Antigen SERINC3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SERINC3
Gene Accession No. Q13530, Q9QZI9
Gene Alias AIGP1, DIFF33, SBBI99, SERINC3, serine incorporator 3, TDE, TDE1, TMS 1
Gene Symbols Serinc3
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10955, 26943, 296350
Target Species Rat, Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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