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  8. SCH-23390 hydrochloride, MedChemExpress

SCH-23390 hydrochloride, MedChemExpress

Product Code. p-200096543
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Product Code. 16477636

Brand: Medchem Express HY19545A

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Description

MedChemExpress SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively.

SCH-23390 hydrochloride is a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT2 and 5-HT1C receptors. SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM.

Specifications

Chemical Name or Material SCH-23390 hydrochloride
CAS 125941-87-9
Color Off-White
Purity Grade Notes Research
Molecular Formula C17H19Cl2NO
Quantity 100 mg
Synonym R-(+)-SCH-23390 hydrochloride
Solubility Information DMSO : ≥ 32 mg/mL (98.69 mM) ∣H2O : 28.57 mg/mL (88.11 mM; Need ultrasonic)
SMILES OC1=C(Cl)C=C2CCN(C)C[C@H](C3=CC=CC=C3)C2=C1.[H]Cl
Molecular Weight (g/mol) 324.24
Formula Weight 324.24
Percent Purity 99.21%
Grade Research
Physical Form Powder
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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