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  6. Samuraciclib hydrochloride, MedChemExpress

Samuraciclib hydrochloride, MedChemExpress

Product Code. 16474936
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Product Code. 16474936

Brand: Medchem Express HY103712A

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Description

MedChemExpress Samuraciclib hydrochloride (CT7001 hydrochloride) is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM.

Samuraciclib hydrochloride displays 45-, 15-, 230- and 30-fold selectivity over CDK1, CDK2 (IC50 of 578 nM), CDK5 and CDK9, respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 μM. Samuraciclib hydrochloride has anti-tumor effects.

Specifications

Chemical Name or Material Samuraciclib hydrochloride
Physical Form Powder
CAS 1805789-54-1
Color White
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C22H31ClN6O
For Use With (Application) Cancer-Kinase/protease
Synonym CT7001 hydrochlorideICEC0942 hydrochloride
Solubility Information H2O : 55 mg/mL (127.62 mM; Need ultrasonic) ∣DMSO : 50 mg/mL (116.02 mM; Need ultrasonic)
SMILES O[C@H]1CNCC[C@@H]1CNC2=NC3=C(C(C)C)C=NN3C(NCC4=CC=CC=C4)=C2.[H]Cl
Molecular Weight (g/mol) 430.97
Formula Weight 430.97
Percent Purity 98.03%
Grade Research
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Research purposes only

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