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RSL3, MedChemExpress

Product Code. p-200099790
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Product Code. 16492848

Brand: Medchem Express HY100218A

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Description

MedChemExpress RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.

RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.

Specifications

Chemical Name or Material RSL3
CAS 1219810-16-8
Color White
Purity Grade Notes Research
Molecular Formula C23H21ClN2O5
Quantity 10 mg
Synonym (1S,3R)-RSL3
Solubility Information DMSO : 250 mg/mL (567.05 mM; Need ultrasonic)
SMILES O=C([C@H]1CC2=C([C@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=C2C=CC=C4)OC
Molecular Weight (g/mol) 440.88
Formula Weight 440.88
Percent Purity 98.1%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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