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Invitrogen™ RPP30 Polyclonal Antibody
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Product Code. 16519911
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Quantity:
100 μL
Unit Size:
100µL
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16519911 100 μL 100µL
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Product Code. 16519911 Supplier Invitrogen™ Supplier No. PA597075

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAVFADLDLR AGSDLKALRG LVETAAHLGY SVVAINHIVD FKEKKQEIEK PVAVSELFTT LPIVQGKSRP IKILTRLTII VSDPSHCNVL RATSSRARLY DVVAVFPKTE KLFHIACTHL DVDLVCITVT EKLPFYFKRP PINVAIDRGL AFELVYSPAI KDSTMRRYTI SSALNLMQIC KGKNVIISSA AERPLEIRGP YDVANLGLLF GLSESDAKAA VSTNCRAALL HGETRKTAFG IISTVKKPRP SEGDEDCLPA SKKAKCEG; Positive Samples: HeLa, Jurkat, HT-1080, HepG2; Cellular Location: Nucleus, nucleolus.

RNase P, which consists of a complex of an RNA species (H1 RNA), POP1 (Processing of Precursor 1), POP5 (Processing of Precursor 5), and at least seven Rpps (including Rpp14, Rpp29, Rpp30 and Rpp38), removes the 5' leader sequences from precursor tRNA molecules. The structurally related RNase MRP plays an essential role in the formation of the 5' end of 5.8S rRNA. Both RNase P and RNase MRP are associated with Th/To ribonucleoproteins; Rpp30 and Rpp38 have specifically been implicated as Th autoantigens which contribute to the autoimmune disease systemic sclerosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RPP30
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.72 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RPP30
Gene Accession No. O88796, P78346
Gene Alias Ribonuclease P protein subunit p30; ribonuclease P/MRP 30 subunit; ribonuclease P/MRP 30kDa subunit; ribonuclease P/MRP subunit; ribonuclease P/MRP subunit p30; ribonuclease P2; RNase P subunit 2; RNaseP protein p30; RNASEP2; RPP30; TSG15
Gene Symbols RPP30
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-268 of human RPP30 (NP_0064041).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10556, 54364, 685332
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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