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RPA/p70 (Replication Protein A) Ab-2, Mouse Monoclonal Antibody,Lab Vision™ Epredia™
Shop All Epredia ProductsDescription
Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase α and δ. RPA70 is composed of three domains: an N-terminal domain that is not required for ssDNA binding or SV40 replication, a central DNA-binding domain, and a C-terminal domain that is essential for subunit interactions.
Host Species: Mouse
Clone: 2H10 or 70C or αSSB70C
Isotype: IgG1/κ
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Purified human RPA protein
Molecular Weight: 70kDa
Positive Control: HeLa cells
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Not suitable)
- Western Blotting
- Immunoprecipitation (Native and denatured)
- Gel Supershift
Note:
USA: RUO; Int'l: RUO
Specifications
Specifications
| Antigen | RPA/p70 (Replication Protein A) Ab-2 |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | 2H10 or 70C or alphaSSB70C |
| Concentration | 200μg/mL |
| Conjugate | Unconjugated |
| Host Species | Mouse |
| Immunogen | Purified human RPA protein |
| Quantity | 500 μL |
| Regulatory Status | RUO |
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