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Ribociclib succinate, MedChemExpress

Product Code. 16489367
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16489367 5 mg 5mg
16462897 50 mg 50mg
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16446828 10 mg 10mg
16401206 200 mg 200mg
16461786 500 mg 500mg
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Product Code. 16489367 Supplier Medchem Express Supplier No. HY15777B

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Description

MedChemExpress Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

Specifications

Chemical Name or Material Ribociclib succinate
CAS 1374639-75-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C27H36N8O5
Quantity 5 mg
Synonym LEE011 succinate
Solubility Information DMSO : 41.67 mg/mL (75.40 mM; Need ultrasonic) ∣H2O : 4.17 mg/mL (7.55 mM; ultrasonic and warming and heat to 60°C)
SMILES O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.OC(CCC(O)=O)=O
Molecular Weight (g/mol) 552.63
Formula Weight 552.63
Percent Purity 98.01%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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