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  6. RHOB Rabbit anti-Human, Mouse, Polyclonal, Proteintech

RHOB Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16812914 Shop All Proteintech Products
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20 μL
150 μL
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150µL
20µL
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16812914 20 μL 20µL
16802914 150 μL 150µL
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Product Code. 16812914 Supplier Proteintech Supplier No. 143261AP20UL

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Description

Rabbit Polyclonal Antibody

RhoB (Rho-related GTP-binding protein) mediates apoptosis in neoplastically transformed cells after DNA damage. While not essential for development, it does affect cell adhesion and growth factor signaling in transformed cells. RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a tumor supressor - deletion of RhoB causes tumor formation.

Specifications

Antigen RHOB
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RHOB
Gene Accession No. P62745, P62746
Gene Alias ARH6, ARHB, h6, MST081, MSTP081, Rho cDNA clone 6, RHOB, RHOH6
Gene Symbols RHOB
Host Species Rabbit
Immunogen RHOB Fusion Protein Ag5593
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11852, 388
Target Species Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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