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RG7112, MedChemExpress

Product Code. 16407037
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Product Code. 16407037

Brand: Medchem Express HY10959

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Description

MedChemExpress RG7112 is a potent, selective, first clinical, orally active and blood-brain barrier crossed MDM2-p53 inhibitor, with an IC50 of 18 nM and a KD of 11 nM for binding to MDM2.

RG7112 is a potent, selective, first clinical, orally active and blood-brain barrier crossed MDM2-p53 inhibitor, with an IC50 of 18 nM and a KD of 11 nM for binding to MDM2.

Specifications

Chemical Name or Material RG7112
CAS 939981-39-2
Color White
Purity Grade Notes Research
Molecular Formula C38H48Cl2N4O4S
Quantity 5 mg
Synonym RO5045337
Solubility Information DMSO : 200 mg/mL (274.81 mM; Need ultrasonic)
SMILES C[C@@]1([C@](C)(N(C(C2=CC=C(C=C2OCC)C(C)(C)C)=N1)C(N3CCN(CC3)CCCS(=O)(C)=O)=O)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Molecular Weight (g/mol) 727.78
Formula Weight 727.78
Percent Purity 99.84%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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