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Resatorvid, MedChemExpress

Product Code. p-200096222
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Quantity:
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100 mg
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Product Code. 16417127

Brand: Medchem Express HY11109

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Description

MedChemExpress Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases.

Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases.

Specifications

Chemical Name or Material Resatorvid
CAS 243984-11-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C15H17ClFNO4S
Quantity 5 mg
Synonym TAK-242 CLI-095
Solubility Information DMSO : 100 mg/mL (276.38 mM; Need ultrasonic)
SMILES O=S([C@H]1C(C(OCC)=O)=CCCC1)(NC2=CC=C(C=C2Cl)F)=O
Molecular Weight (g/mol) 361.82
Formula Weight 361.82
Percent Purity 98.04%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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