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Description
DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similiar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA
Specifications
Specifications
| Antigen | RBM6 |
| Applications | Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.18 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | RBM6 |
| Gene Accession No. | P78332 |
| Gene Alias | 3G2, DEF 3, DEF3, g16, HLC 11, Lung cancer antigen NY LU 12, NY LU 12, Protein G16, RBM6, RNA binding motif protein 6, RNA binding protein 6, RNA binding protein DEF 3 |
| Gene Symbols | Rbm6 |
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Product Title
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