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Invitrogen™ RASSF1 Polyclonal Antibody
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100 μL
Unit Size:
100µL
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15767131 100 μL 100µL
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Product Code. 15767131 Supplier Invitrogen™ Supplier No. PA559273

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KFTCHYRCRA LVCLDCCGPR DLGWEPAVER DTNVDEPVEW ETPDLSQAEI EQKIKEYNAQ INSNLFMSLN KDG Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASSF1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RASSF1
Gene Accession No. Q9NS23
Gene Alias 123F protein; 123F2; AA536941; AU044980; cardiac-specific ras association domain family 1 protein; NORE2A; pancreas-specific ras association domain family 1 protein; protein 123F2; Ras association (RalGDS/AF-6) domain family 1; Ras association (RalGDS/AF-6) domain family member 1; Ras association domain family 1; Ras association domain family member 1; ras association domain-containing protein 1; Rassf1; Rassf1A; RASSF1A tumor suppressor; Rassf1B; Rassf1C; RDA32; REH3P21; tumor suppressor protein RDA32; wu:fc17f02; WUGSC:H_LUCA12.5; zgc:112224; zgc:92505; zgc:92505 protein
Gene Symbols RASSF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RASSF1. Recombinant protein control fragment (Product #RP-98331).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11186
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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