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Invitrogen™ RASA4 Polyclonal Antibody
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Product Code. 17148203
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Quantity:
100 μL
Unit Size:
100µL
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17148203 100 μL 100µL
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Product Code. 17148203 Supplier Invitrogen™ Supplier No. PA5110274

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HLPPTFHAVA FYVMDEDALS RDDVIGKVCL TRDTIASHPK GFSGWAHLTE VDPDEEVQGE IHLRLEVWPG ARACRLRCSV LEARDLAPKD RNGTSDPFVR VRYKGRTRET SIVKKSCYPR WNETFEFELQ EGAMEALCVE AWDWDLVSRN DFLGKVVIDV QRLRVVQQEE GWFRLQPDQS KSRRHDEGNL GSLQLEVRLR DETVLPSSYY QPLVHLLCHE VKLGMQGPGQ L.

This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASA4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.74 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RASA4
Gene Accession No. O43374, Q6PFQ7
Gene Alias AA793972; AW112107; BB079060; Ca2+promoted Ras inactivator; Ca2+-promoted Ras inactivator; calcium-promoted RAS inactivator; Capri; GAPL; Kiaa0538; Ras GTPase-activating protein 4; RAS p21 protein activator 4; RASA4; RasGAP-activating-like protein 2; RGD1565457
Gene Symbols RASA4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 60-290 of human RASA4 (NP_008920.5).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10156, 288589, 54153
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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