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Description
Immunogen sequence: VIYGKGVVCT LHEGDDFGKL ALVNDAPRAA SIVLREDNCH FLRVDKEDFN RILRDVEANT VRLKEHDQDV LVLEKVPAGN RASNQGNSQP QQKYTVMSGT PEKILEHFLE TIRLEATLNE ATDSVLNDFI MMHCVFMPNT QLC Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.
Specifications
Specifications
| Antigen | RAPGEF4 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Rapgef4 |
| Gene Accession No. | Q8WZA2 |
| Gene Alias | 1300003D15Rik; 5730402K07Rik; 6330581N18Rik; cAMP-dependent Rap1 guanine-nucleotide exchange factor; cAMP-GEFII; cAMP-regulated guanine nucleotide exchange factor II; cAMP-regulated guanine nucleotide exchange factor IIB; CAMPS; Cgef2; EPAC; epac 2; Epac2; Epac-2; Exchange factor directly activated by cAMP 2; exchange protein directly activated by cAMP 2; gefii; mKIAA4040; Nbla00496; putative protein product of Nbla00496; Rap guanine nucleotide exchange factor (GEF) 4; Rap guanine nucleotide exchange factor 4; RAP guanine-nucleotide-exchange factor (GEF) 4; Rapgef4 |
| Gene Symbols | Rapgef4 |
| Show More |
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