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Invitrogen™ RAMP1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA550253

Product Code. 15644185

  • 524.00 EUR / 100µL

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Description

Description

The antibody detects endogenous levels of total RAMP1 protein.

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

RAMP1
Polyclonal
Unconjugated
RAMP1
9130218E19Rik; calcitonin receptor-like receptor activity modifying protein 1; calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1; MGC38240; RAMP1; receptor (calcitonin) activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1; receptor activity modifying protein 1; receptor activity-modifying protein 1
Rabbit
Antigen affinity chromatography
RUO
10267, 51801, 58965
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.4 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
O60894, Q9JJ74, Q9WTJ5
RAMP1
Fusion protein corresponding to a region derived from internal residues of human Receptor (G protein-coupled) activity modifying protein 1.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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