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IGF1R (phospho Y1346), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Product Code. 16284280
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Quantity:
100 μL
Unit Size:
100µL
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16284280 100 μL 100µL
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Product Code. 16284280 Supplier Abnova Supplier No. PAB29290.100uL

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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF1R.

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq

Specifications

Antigen IGF1R
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF1R.
Dilution Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene IGF1R
Gene Alias CD221/IGFIR/JTK13/MGC142170/MGC142172/MGC18216
Gene Symbols IGF1R
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1346 of human IGF1R.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3480
Test Specificity IGF1R (phospho Y1346) polyclonal antibody detects endogenous levels of human IGF1R only when phosphorylated at tyrosine 1346.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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