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R&D Systems™ Quantikine Control Group 256 for Human LIF, DLF00B
Description
- Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines.
- Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation.
- Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts.
- The activities of LIF are mediated through a high-affinity heterodimeric receptor complex consisting of two membrane glycoproteins:
- an alpha subunit (LIF R alpha, also known as LIF R beta and CD118) that binds LIF with low affinity
- and the 130 kDa (gp130) subunit that does not bind LIF by itself, but is required for high-affinity binding of LIF by the complex
Specifications
Specifications
| Product Type | ELISA |
| For Use With (Equipment) | Catalog number DLF00B |
| Gene ID (Entrez) | 3976 |
| Host Species | Human |
| Quantity | 1 Each |
| Storage Requirements | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
| Target | LIF |
Product Title
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