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Invitrogen™ PIG3 Recombinant Rabbit Monoclonal Antibody (026)
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Product Code. 17169125
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Quantity:
100 μL
Unit Size:
100µL
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17169125 100 μL 100µL
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Product Code. 17169125 Supplier Invitrogen™ Supplier No. MA529873

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Description

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human PIG3/TP53I3.

The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIG3
Applications ELISA
Classification Recombinant Monoclonal
Clone 026
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene TP53I3
Gene Accession No. Q53FA7
Gene Alias p53-induced gene 3 protein; PIG3; quinone oxidoreductase homolog; quinone oxidoreductase PIG3; Quinone oxidoreductase-like protein 2; RGD1304982; TP53I3; tumor protein p53 inducible protein 3; Tumor protein p53-inducible protein 3
Gene Symbols TP53I3
Host Species Rabbit
Immunogen Recombinant Human PIG3/TP53I3 Protein (Met1-Gln332).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9540
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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