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PI-103 Hydrochloride, MedChemExpress

Product Code. 16479826
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Product Code. 16479826 Supplier Medchem Express Supplier No. HY10115A

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Description

MedChemExpress PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy.

PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy.

Specifications

Chemical Name or Material PI-103 Hydrochloride
CAS 371935-79-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C19H17ClN4O3
Quantity 50 mg
Solubility Information DMSO : 4.1 mg/mL (10.65 mM; Need ultrasonic and warming) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES OC1=CC(C2=NC3=C(OC4=C3C=CC=N4)C(N5CCOCC5)=N2)=CC=C1.[H]Cl
Molecular Weight (g/mol) 384.82
Formula Weight 384.82
Percent Purity 96.37%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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