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Invitrogen™ Phospho-YAP1 (Ser127) Polyclonal Antibody

Product Code. 11532380
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Quantity:
100 μL
Unit Size:
100µL
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11532380 100 μL 100µL
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Product Code. 11532380 Supplier Invitrogen™ Supplier No. PA517481

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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-YAP1 (Ser127)
Applications Western Blot
Classification Polyclonal
Concentration 59.2 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene YAP1
Gene Accession No. P46937, P46938, Q2EJA0
Gene Alias 65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP
Gene Symbols YAP1
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pSer127 of human YAP.
Purification Method Protein A, Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10413, 22601, 363014
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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