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Invitrogen™ Phospho-WNK1 (Thr60) Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA536701

Product Code. 15524011

  • 520.00 EUR / 100µL

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Description

Description

This antibody detects endogenous protein at a molecular weight of 230 kDa. Purity is >95% by SDS-PAGE.

WNK1 serine/threonine kinase is a member of the WNK subfamily. WNK1 may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. WNK plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-WNK1 (Thr60)
Polyclonal
Unconjugated
WNK1
6430573H23Rik; EG406236; Erythrocyte 65 kDa protein; HSAN2; HSN2; hWNK1; KDP; KIAA0344; Kinase deficient protein; MGC163339; MGC163341; mKIAA0344; p65; PPP1R167; Prkwnk1; prostate-derived sterile 20-like kinase; protein kinase lysine-deficient 1; Protein kinase with no lysine 1; protein phosphatase 1, regulatory subunit 167; PSK; Serine/threonine-protein kinase WNK1; serine/threonine-protein kinase WNK1 1; serine/threonine-protein kinase WNK1 2; With no K; WNK lysine deficient protein kinase 1; WNK lysine deficient protein kinase 1 isoform; WNK1
Rabbit
Antigen affinity chromatography
RUO
116477, 232341, 65125
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
P83741, Q9H4A3, Q9JIH7
WNK1
Synthetic phosphopeptide derived from human WNK1 around the phosphorylation site of Threonine 60.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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