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Invitrogen™ Phospho-TTK (Thr676) Polyclonal Antibody
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Product Code. 16642365
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Quantity:
100 μL
Unit Size:
100µL
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16642365 100 μL 100µL
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Product Code. 16642365 Supplier Invitrogen™ Supplier No. PA5105923

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of TTK only when phosphorylated at Thr676.

TTK is a serine/threonine kinase closely related to SPK1, PIM 1 and CDC2 serine/threonine kinases. TTK is a dual-specificity kinase, which can also phosphorylate tyrosine. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. TTK encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TTK (Thr676)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TTK
Gene Accession No. P33981, P35761
Gene Alias AL022661; cancer/testis antigen 96; CT96; Dual specificity protein kinase TTK; esk; Esk1; monopolar spindle 1 kinase; monopolar spindle 1-like 1; MPH1; MPS1; MPS1L1; OTTHUMP00000016778; OTTHUMP00000220743; phosphotyrosine picked threonine kinase; phosphotyrosine picked threonine-protein kinase; PYT; TTK; Ttk protein kinase
Gene Symbols TTK
Host Species Rabbit
Immunogen A synthesized peptide derived from human TTK(Accession P33981), corresponding to amino acid residues around phosphorylated Thr676.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22137, 315852, 7272
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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