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Invitrogen™ Phospho-TOP2A (Ser1337) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5118788
This item is not returnable.
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Description
Antibody detects endogenous levels of TOP2A only when phosphorylated at Ser1337.
Topo II alpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2 and M-phases in transformed and developmentally regulated normal cellsTopo II alpha is also implicated in drug resistance of tumor cells.
Specifications
| Phospho-TOP2A (Ser1337) | |
| Polyclonal | |
| Unconjugated | |
| TOP2A | |
| DNA gyrase; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha-like protein; DNA Topoisomerase II alpha; DNA topoisomerase II, 170 kD; DNA topoisomerase II, alpha isozyme; EC 5.99.1.3; OTTHUMP00000207108; P11388-1; TOP2; Top-2; Top2a; TOPOII; topoisomerase (DNA) 2 alpha; topoisomerase (DNA) II alpha; topoisomerase (DNA) II alpha 170kDa; topoisomerase ii alpha; topoisomersae II; TP2A | |
| Rabbit | |
| Sequential chromatography | |
| RUO | |
| 21973, 360243, 7153 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P11388, P41516, Q01320 | |
| TOP2A | |
| A synthesized peptide derived from human TOP2A(Accession P11388), corresponding to amino acid residues around phosphorylated Ser1337. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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