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Invitrogen™ Phospho-Synaptotagmin 1/2 (Ser309) Polyclonal Antibody
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Product Code. 16654355
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Quantity:
100 μL
Unit Size:
100µL
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16654355 100 μL 100µL
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Product Code. 16654355 Supplier Invitrogen™ Supplier No. PA5104839

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Synaptotagmin 1/2 only when phosphorylated at Serine 309.

Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus.
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Specifications

Antigen Phospho-Synaptotagmin 1/2 (Ser309)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SYT1
Gene Accession No. P21579, P21707, P29101, P46096, P46097, Q8N9I0
Gene Alias AW124717; CMS7; FLJ42519; G630098F17Rik; Inositol polyphosphate-binding protein; IP4-binding protein; mKIAA4194; MYSPC; p65; R74640; RATSYNII; SVP65; synaptotagmin 1; synaptotagmin 2; synaptotagmin I; Synaptotagmin II; synaptotagmin-1; Synaptotagmin-2; SYNII; SYT; SYT1; SYT2; SytI; sytII
Gene Symbols SYT1, SYT2
Host Species Rabbit
Immunogen A synthesized peptide derived from human SYT1(Accession P21579), corresponding to amino acid residues around phosphorylated Ser309.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 127833, 20979, 20980, 24805, 25716, 6857
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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