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  6. Invitrogen™ Phospho-Rb (Ser807, Ser811) Recombinant Rabbit Monoclonal Antibody (RbS807S811-D9), Invitrogen™

Invitrogen™ Phospho-Rb (Ser807, Ser811) Recombinant Rabbit Monoclonal Antibody (RbS807S811-D9), Invitrogen™

Product Code. 17116838 Shop All Thermo Scientific Products
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200 μL
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17116838 20 μL 20µL
17196528 200 μL 200µL
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Product Code. 17116838 Supplier Invitrogen™ Supplier No. MA537245

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Description

Rabbit Recombinant Monoclonal Antibody

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Rb (Ser807, Ser811)
Applications Flow Cytometry, Western Blot
Classification Recombinant Monoclonal
Clone RbS807S811-D9
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide
Gene RB1
Gene Accession No. P06400, P13405
Gene Alias Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein
Gene Symbols RB1
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Ser807/Ser811 of human phospho Rb.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19645, 5925
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG κ
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