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Phospho-NIPA (Ser354) Polyclonal Antibody, Invitrogen™

Product Code. 15595691
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Quantity:
100 μg
Unit Size:
100µg
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15595691 100 μg 100µg
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Product Code. 15595691 Supplier Invitrogen Supplier No. PA538782

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Description

Rabbit Polyclonal Antibody

Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-NIPA (Ser354)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ZC3HC1
Gene Accession No. Q86WB0, Q80YV2
Gene Alias 1110054L24Rik, NIPA, hNIPA, hematopoietic stem/progenitor cell protein 216, nuclear interacting partner of anaplastic lymphoma kinase (ALK), nuclear interaction partner of ALK, nuclear-interacting partner of ALK, nuclear-interacting partner of anaplastic lymphoma kinase, zinc finge
Gene Symbols ZC3HC1
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human NIPA around the phosphorylation site of Ser354 (T-R-SP-W-D)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 232679, 296957, 51530
Target Species Human, Mouse, Non-human Primate, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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