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PHGDH Mouse anti-Human, CoraLite 488, Clone: 1E8B8, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech CL488-67591-100UL
Description
PHGDH(D-3-phosphoglycerate dehydrogenase) is also named as 3-PGDH, PGDH3 and belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. It catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor. 3-PGDH deficiency is a rare recessive inborn error in the biosynthesis of the amino acid L-serine characterized clinically by congenital microcephaly, psychomotor retardation, and intractable seizures(PMID:19235232 ).
Specifications
| PHGDH | |
| Monoclonal | |
| 1000 μg/mL | |
| Mouse | |
| Primary | |
| Human, Mouse, Rat, Pig | |
| IgG1 |
| Immunofluorescence | |
| 1E8B8 | |
| CoraLite 488 | |
| 100 μL | |
| 26227 | |
| Liquid |
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