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PFI-2 hydrochloride, MedChemExpress

Product Code. 16453567
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Product Code. 16453567 Supplier Medchem Express Supplier No. HY18627A

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Description

MedChemExpress PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis.

PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis.

Specifications

Chemical Name or Material PFI-2 hydrochloride
CAS 1627607-87-7
Color White
Purity Grade Notes Research
Molecular Formula C23H26ClF4N3O3S
Quantity 50 mg
Synonym (R)-PFI-2 hydrochloride
Solubility Information DMSO : ≥ 32 mg/mL (59.70 mM) ∣H2O : 5.56 mg/mL (10.37 mM; Need ultrasonic)
SMILES O=S(C1=CC2=C(CNCC2)C(F)=C1)(N[C@H](CC3=CC=CC(C(F)(F)F)=C3)C(N4CCCC4)=O)=O.[H]Cl
Molecular Weight (g/mol) 535.98
Formula Weight 535.98
Percent Purity 96.09%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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