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PF-4136309, MedChemExpress

Product Code. 16408287
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Quantity:
5 mg
10 mg
50 mg
Unit Size:
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50mg
5mg
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Product Code. 16408287

Brand: Medchem Express HY13245

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Description

MedChemExpress PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.

PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.

Specifications

Chemical Name or Material PF-4136309
CAS 1341224-83-6
Color Off-White
Purity Grade Notes Research
Molecular Formula C29H31F3N6O3
Quantity 5 mg
Synonym INCB8761
Solubility Information Ethanol : 133.33 mg/mL (234.49 mM; Need ultrasonic) ∣DMSO : ≥ 34 mg/mL (59.80 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES O[C@]1(CC[C@](CC1)([H])N[C@@H]2CN(CC2)C(CNC(C3=CC=CC(C(F)(F)F)=C3)=O)=O)C4=NC=C(C=C4)C5=NC=CC=N5
Molecular Weight (g/mol) 568.59
Formula Weight 568.59
Percent Purity 96.12%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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