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Invitrogen™ PEN2 Recombinant Rabbit Monoclonal Antibody (6J5O4)
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Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA538177

Product Code. 17237053

  • 506.00 EUR / 100µL

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Description

Description

Positive Samples: 293T, A-549, SH-SY5Y, Mouse kidney, Rat lung Immunogen sequence: MNLERVSNEE KLNLCRKYYL GGFAFLPFLW LVNIFWFFRE AFLVPAYTEQ SQIKGYVWRS AVGFLFWVIV LTSWITIFQI YRPRWGALGD YLSFTIPLGT P.

Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PEN2
Recombinant Monoclonal
1.5 mg/mL
PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3
Q6QI68, Q9CQR7, Q9NZ42
PSENEN
Recombinant protein (or fragment)
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
ELISA, Western Blot, Immunocytochemistry
6J5O4
Unconjugated
PSENEN
1700023M09Rik; gamma-secretase subunit PEN-2; hematopoietic stem/progenitor cells protein MDS033; liver regeneration-related protein LRRGT00140; LRRGT00140 mRNA; MDS033; MSTP064; Pen2; Pen-2; presenilin enhancer 2; presenilin enhancer 2 homolog; presenilin enhancer 2 homolog (C. elegans); presenilin enhancer gamma secretase subunit; presenilin enhancer gamma-secretase subunit; presenilin enhancer protein 2; presenilin enhancer, gamma-secretase subunit; Psenen; RGD1312037
Rabbit
Affinity chromatography
RUO
292788, 55851, 66340
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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