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Invitrogen™ PDE10A Polyclonal Antibody

Description
Recommended positive controls: HCT116, mouse brain, rat brain, Myc-DDK-tagged PDE10A-transfected 293T. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate.
Specifications
Specifications
| Antigen | PDE10A |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gene | PDE10A |
| Gene Accession No. | Q8CA95, Q9QYJ6, Q9Y233 |
| Gene Alias | ADSD2; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dJ416F21.1 (phosphodiesterase 10A); dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase; FLJ11894; FLJ25677; HSPDE10A; IOLOD; LINC00473; PDE10A; PDE10A19; PDE10A2 brain-specific isoform; Pde10a3; phosphodiesterase 10A; phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7); testis-specific phosphodiesterase PDE10A2 |
| Gene Symbols | PDE10A |
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