missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Lines and Blood Products
  4. Cell Lines and Cell Cultures
  5. General Cell Lines and Cell Cultures
  6. 17373939

DiscoverX PathHunter™ U2OS EphA4 Functional Assay

Product Code. 17373939
Encompass
Change view
Click to view available options
Quantity:
2 Vials
Unit Size:
2 ampoules
Product Code. Quantity unitSize
17373939 2 Vials 2 ampoules
1 options
This item is not returnable. View return policy

Product Code. 17373939

Brand: DiscoverX 930877C3

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

The PathHunter™ U2OS EphA4 Functional Assay measures EphA4 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ U2OS EphA4 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphA4 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses PK-tagged EphA4 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry U2OS
Cell Line U2OS
For Use With (Application) Cell Lines
Primary Agonist EphrinA3
Quantity 2 Vials
Target Entry EphA4
Accession Number NM_004438.3
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.