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Invitrogen™ PARP16 Polyclonal Antibody

Product Code. 17157013
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
17157013 100 μL 100µL
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Product Code. 17157013 Supplier Invitrogen™ Supplier No. PA5107208

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Description

Rabbit Polyclonal Antibody

Sequence homology: Cow: 79%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 80%; Rabbit: 86%; Rat: 86%.

Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PARP16
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene PARP16
Gene Accession No. Q8N5Y8
Gene Alias ADP-ribosyltransferase diphtheria toxin-like 15; ARTD15; BC055447; C15orf30; C79952; LRRGT00109; mono [ADP-ribose] polymerase PARP16; PARP16; PARP-16; pART15; poly (ADP-ribose) polymerase family, member 16; poly [ADP-ribose] polymerase 16; poly(ADP-ribose) polymerase family member 16; Protein mono-ADP-ribosyltransferase PARP16; RGD1306243
Gene Symbols PARP16
Host Species Rabbit
Immunogen Synthetic peptide located within the following region: PKYFVVTNNQ LLRVKYLLVY SQKPPKSRAS SQLSWFSSHW FTVMISLYLL.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54956
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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