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Palbociclib, MedChemExpress

Product Code. 16494017
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Product Code. 16494017 Supplier Medchem Express Supplier No. HY50767

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Description

MedChemExpress Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Specifications

Chemical Name or Material Palbociclib
CAS 571190-30-2
Color Yellow
Purity Grade Notes Research
Molecular Formula C24H29N7O2
Quantity 50 mg
Synonym PD 0332991
Solubility Information DMSO : 25 mg/mL (55.86 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C) ∣0.1 M HCL : 25 mg/mL (55.86 mM; ultrasonic and adjust pH to 4 with 0.1 M HCL) ∣H2O : 0.1 mg/mL (0.22 mM; Need ultrasonic)
SMILES O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(N5CCNCC5)C=N4)C
Molecular Weight (g/mol) 447.53
Formula Weight 447.53
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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