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Invitrogen™ P2X6 Polyclonal Antibody
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Product Code. 16556101
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Quantity:
100 μL
Unit Size:
100µL
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16556101 100 μL 100µL
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Product Code. 16556101 Supplier Invitrogen™ Supplier No. PA587659

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WGLLDYKTEK WALLAKKGYQ ERDLEPQFSI ITKLKGVSVT QIKELGNRLW DVADFVKPPQ GENVFFLVTN FLVTPAQVQG RCPEHPSVPL ANCWVDEDCP EGEGGTHSHG VKTGQCVVFN GTHRTCEIWS WCPVESGVVP SRPLLAQAQN FTLFIKNTVT FSKFNFSKSN ALETWDPTYF KHCRYEPQFS PYCPVFRIGD LVAKAGGTFE DLALLGGSVG IRVHWDCDLD TGDSGCWPHY SFQLQEKSYN FRTATHWWEQ P; Positive Samples: Mouse pancreas; Cellular Location: Membrane, Multi-pass membrane protein.

P2rx6 encodes receptors that are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each P2rx6 receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains. The protein encoded by the P2rx6 gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. The P2rx6 gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants of P2rx6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen P2X6
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene P2RX6
Gene Accession No. O54803
Gene Alias ATP receptor; P2RX6; P2RXL1; P2X purinoceptor 6; P2x6; P2X6 receptor; P2XM; Purinergic receptor; purinergic receptor P2X 6; purinergic receptor P2X, ligand gated ion channel, 6; purinergic receptor P2X, ligand-gated ion channel, 6; purinergic receptor P2X6; Purinergic receptor P2X-like 1; purinergic receptor P2X-like 1 orphan receptor; purinergic receptor P2X-like 1, orphan receptor; purinoceptor P2X6; purinoreceptor P2X6; Rnap2x6; skeletal muscle-expressed P2X
Gene Symbols P2RX6
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human P2RX6 (NP_0011530261).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18440
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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