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Invitrogen™ OX40L Monoclonal Antibody (OX89)
Rat Monoclonal Antibody
Brand: Invitrogen™ MA517910
This item is not returnable.
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Description
MA5-17910 targets CD134L/OX40L in FACS, FN, and IHC applications and shows reactivity with Mouse samples. The MA5-17910 immunogen is cD4.CD134L chimeric protein.
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
Specifications
| OX40L | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| P43488 | |
| Tnfsf4 | |
| CD4.CD134L chimeric protein. | |
| 250 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Functional Assay, Immunohistochemistry | |
| OX89 | |
| Unconjugated | |
| Tnfsf4 | |
| Ath1; Ath-1; atherosclerosis 1; CD134 ligand; CD134L; CD252; glycoprotein Gp34; GP34; OX40 antigen ligand; OX40 ligand; OX40L; OX-40L; OX4OL; TAX transcriptionally-activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 (34kD); tax-transcriptionally activated glycoprotein 1 ligand; TNFSF4; TNLG2B; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor (ligand) superfamily, member 4; tumor necrosis factor ligand 2B; tumor necrosis factor ligand superfamily member 4; tumor necrosis factor superfamily member 4; TXGP1; Txgp1l | |
| Rat | |
| Protein G | |
| RUO | |
| 22164 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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