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Oncrasin 1, Tocris Bioscience™

Product Code. 18075582
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Product Code. 18075582 Supplier Tocris Bioscience Supplier No. 3427/10

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Description

Induces abnormal nuclear aggregation of PKCι; proapoptotic

Proapoptotic agent that induces abnormal nuclear aggregation of PKCι and suppresses RNA transcription. Exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC50 ≤ 3 μM) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 75629-57-1
Molecular Formula C16H12ClNO
Molecular Weight (g/mol) 269.73
MDL Number MFCD01051808
InChI Key ZDRQMXCSSAPUMM-UHFFFAOYSA-N
Synonym oncrasin-1, 1-4-chlorobenzyl-1h-indole-3-carbaldehyde, oncrasin 1, 1-4-chlorophenyl methyl indole-3-carbaldehyde, 1-4-chlorophenyl methyl-1h-indole-3-carboxaldehyde, 1-4-chloro-benzyl-1h-indole-3-carbaldehyde, oncrasin1, cambridge id 5601604, n-4-chlorobenzyl-3-formylindole, oncrasin hplc
PubChem CID 872445
IUPAC Name 1-[(4-chlorophenyl)methyl]-1H-indole-3-carbaldehyde
SMILES ClC1=CC=C(CN2C=C(C=O)C3=CC=CC=C23)C=C1

Specifications

Quantity 10 mg
Formula Weight 269.73
Percent Purity >98%
Chemical Name or Material Oncrasin 1
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