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NXT629, MedChemExpress

Product Code. 16477547
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16477547 5 mg 5mg
16471067 50 mg 50mg
16415606 100 mg 100mg
16414808 10 mg 10mg
16403256 25 mg 25mg
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Product Code. 16477547 Supplier Medchem Express Supplier No. HY114263

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Description

MedChemExpress NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

Specifications

Chemical Name or Material NXT629
CAS 1454925-59-7
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C35H39N5O3S
Quantity 5 mg
Solubility Information DMSO : 125 mg/mL (204.99 mM; Need ultrasonic)
SMILES O=S(C1=CC=CC=C1)(NC2=CC=C(C3=CC=C(CCCC(N4CC)=NN(CC5=CC=C(C(C)(C)C)C=C5)C4=O)C=C3)N=C2)=O
Molecular Weight (g/mol) 609.78
Formula Weight 609.78
Percent Purity 99.2%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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