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NVP-TAE 226, MedChemExpress
Description
NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively.
Specifications
Specifications
| Chemical Name or Material | NVP-TAE 226 |
| CAS | 761437-28-9 |
| Color | Yellow |
| Purity Grade Notes | Research |
| Molecular Formula | C23H25ClN6O3 |
| Quantity | 100 mg |
| Synonym | TAE226 |
| Solubility Information | DMSO : 50 mg/mL (106.62 mM; Need ultrasonic) |
| SMILES | O=C(C1=C(C=CC=C1)NC2=NC(NC3=C(C=C(C=C3)N4CCOCC4)OC)=NC=C2Cl)NC |
| Molecular Weight (g/mol) | 468.94 |
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Research purposes only
Product Title
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