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NVP-TAE 226, MedChemExpress

Product Code. 16475548
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Código de producto. 16475548 Proveedor Medchem Express N.º de proveedor HY13203

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Descripción

MedChemExpress NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively.

NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively.

Especificaciones

Chemical Name or Material NVP-TAE 226
CAS 761437-28-9
Color Yellow
Purity Grade Notes Research
Molecular Formula C23H25ClN6O3
Quantity 10 mg
Synonym TAE226
Solubility Information DMSO : 50 mg/mL (106.62 mM; Need ultrasonic)
SMILES O=C(C1=C(C=CC=C1)NC2=NC(NC3=C(C=C(C=C3)N4CCOCC4)OC)=NC=C2Cl)NC
Molecular Weight (g/mol) 468.94
Formula Weight 468.94
Percent Purity 99.22%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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