missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Phenoxy compounds
  8. Nutlin-3a, MedChemExpress

Nutlin-3a, MedChemExpress

Product Code. 16405657
Encompass_Preferred
Click to view available options
Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
This item is not returnable. View return policy

Product Code. 16405657

Brand: Medchem Express HY10029

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Nutlin-3a (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas.

Nutlin-3a (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas.

Specifications

Chemical Name or Material Nutlin-3a
CAS 675576-98-4
Color White
Purity Grade Notes Research
Molecular Formula C30H30Cl2N4O4
Quantity 5 mg
Synonym Rebemadlin
Solubility Information DMSO : ≥ 100 mg/mL (171.97 mM)
SMILES O=C(N1C(C2=C(C=C(C=C2)OC)OC(C)C)=N[C@H]([C@H]1C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)Cl)N5CC(NCC5)=O
Molecular Weight (g/mol) 581.49
Formula Weight 581.49
Percent Purity 96.42%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.