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NKX2.2 Antibody (NX2/294), Alexa Fluor™ 532, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-33058AF532

Product Code. 18103182

  • 587.00 EUR / 0.10mL

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Description

Description

NKX2.2 Monoclonal specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NKX2.2
Monoclonal
Alexa Fluor 532
50 mM sodium borate with 0.05% sodium azide
NKX2-2
Human full-length recombinant NKX2.2 protein (Uniprot: O95096)
0.1 mL
4821.0
Human, Mouse, Rat, Chicken
IgG2b κ
ELISA
NX2/294
ELISA
Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B
Mouse
Protein A or G purified
Primary
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Store at 4°C in the dark.
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