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Description
Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
Specifications
Specifications
| Antigen | NIT1 |
| Applications | Immunofluorescence, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.15 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | NIT1 |
| Gene Accession No. | Q7TQ94, Q86X76, Q8VDK1 |
| Gene Alias | NIT1, nitrilase 1, Nitrilase homolog 1 |
| Gene Symbols | Nit1 |
| Show More |
Product Title
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