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Invitrogen™ NFKBIL1 Polyclonal Antibody
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Product Code. 13207378
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Quantity:
100 μg
Unit Size:
100µg
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13207378 100 μg 100µg
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Product Code. 13207378 Supplier Invitrogen™ Supplier No. PA523499

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Description

Rabbit Polyclonal Antibody

Suggested positive control: HeLa. The amino acid sequence used as immunogen is 100% homologous in new world monkey, panda, mouse lemur, chimpanzee, orangutan, rhesus monkey, wild pig, 95% homologous in horse, rat, mouse, 89% homologous in frog, opossum, sea anemone and 74% homologous in platypus and carolina anole. Reacts with Frog. Immunogen sequence: RRYLRVQQVR WHPDRFLQR.

NF-kappa-B inhibitor-like protein 1 (NFKBIL1), also named Ikb like and IkbL1, is a 381 amino acid member of the inhibitor of NF-kappaB (IkappaB) family of proteins. NFKBIL1 contains two ANK repeats and is expressed in the rheumatoid synovial lining and sub-lining layers and co-localized in CD68+ and CD3+, but not Factor VIII+ cells. It is reported that defects in NFKBIL1 expression causes of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and affects the joints. Rheumatoid arthritis (RA) is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFKBIL1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene NFKBIL1
Gene Accession No. Q861W0, Q9UBC1
Gene Alias DADB-70P7.2; Def-7; ikappaBL; I-kappa-B-like protein; Ikbl; Inhibitor of kappa B-like protein; LST1; NF-kappa-B inhibitor-like protein 1; NFKB inhibitor like 1; NFKBIL; NFKBIL1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
Gene Symbols NFKBIL1
Host Species Rabbit
Immunogen Human NFKBIL1 (aa 331-349).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100050027, 462558, 4795, 481711, 514369
Target Species Human, Canine, Monkey, Bovine, Horse, Amphibian, Chimpanzee
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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