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Invitrogen™ N-cadherin Monoclonal Antibody (CH-19)
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Product Code. 11571112
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
11571112 100 μL 100µL
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Product Code. 11571112 Supplier Invitrogen™ Supplier No. MA191128

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Description

Mouse Monoclonal Antibody

Recommended positive controls: MDBK. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.
TRUSTED_SUSTAINABILITY

Specifications

Antigen N-cadherin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone CH-19
Concentration 6.1 mg/mL
Conjugate Unconjugated
Formulation Ascites with 15mM sodium azide
Gene CDH2
Gene Accession No. O55075, P10288, P15116, P19022, P19534, Q9Z1Y3
Gene Alias bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD
Gene Symbols CDH2
Host Species Mouse
Immunogen Synthetic peptide corresponding to the C-terminal amino acids of chicken N-Cadherin with an extra N-terminal lysine residue (24 amino acids) coupled to KLH.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1000, 100170321, 100344571, 100515322, 100689204, 100714783, 101082701, 102188004, 12558, 281062, 414745, 480169, 83501
Target Species Human, Mouse, Rat, Canine, Rabbit, Bovine, Sheep, Hamster, Pig, Feline, Chicken, Chicken, Guinea Pig, Reptile, Rodent, Goat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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